000014151 001__ 14151 000014151 005__ 20161115100143.0 000014151 04107 $$aeng 000014151 046__ $$k2016-08-21 000014151 100__ $$aHedrih, Andjelka 000014151 24500 $$aZona pelucida as a mechano-responsive polymer 000014151 24630 $$n24.$$p24th International Congress of Theoretical and Applied Mechanics - Book of Papers 000014151 260__ $$bInternational Union of Theoretical and Applied Mechanics, 2016 000014151 506__ $$arestricted 000014151 520__ $$2eng$$aZona pelucida (ZP) is the most outer structure of mammalian oocytes and is important for gamete recognition, fertilization and integrity of the embryo. ZP is highly sulfated and glycosylated polymer gel that exhibit visco-elastic properties. Temperature, pH, ionic strength influences its biological function and aggregate state. We consider ZP as mechano-responsive polymer and proposed a new theory of fertilization based on coupled chemical²electrical fields and modeled ZP as a non-linear oscillatory reactive system. Analysis of its oscillatory states regarding external force is discussed. 000014151 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb. 000014151 653__ $$a 000014151 7112_ $$a24th International Congress of Theoretical and Applied Mechanics$$cMontreal (CA)$$d2016-08-21 / 2016-08-26$$gICTAM2016 000014151 720__ $$aHedrih, Andjelka 000014151 8560_ $$ffischerc@itam.cas.cz 000014151 8564_ $$s148933$$uhttps://invenio.itam.cas.cz/record/14151/files/PO.SM01-1.07.198.pdf$$yOriginal version of the author's contribution as presented on CD, page 1719, code PO.SM01-1.07.198 . 000014151 962__ $$r13812 000014151 980__ $$aPAPER