000014403 001__ 14403
000014403 005__ 20161115100150.0
000014403 04107 $$aeng
000014403 046__ $$k2016-08-21
000014403 100__ $$aCoupier, Gwennou
000014403 24500 $$aInversion of hematocrit partition at microfluidic bifurcations

000014403 24630 $$n24.$$p24th International Congress of Theoretical and Applied Mechanics - Book of Papers
000014403 260__ $$bInternational Union of Theoretical and Applied Mechanics, 2016
000014403 506__ $$arestricted
000014403 520__ $$2eng$$aPartitioning of red blood cells (RBCs) at the level of bifurcations in the microcirculatory system affects many physiological functions yet it remains poorly understood. We address this problem by using T—shaped microfluidic bifurcations as a model. Our computer simulations and in vitro experiments reveal that the hematocrit ((1)0) partition depends strongly on RBC deformability, as long as (1)0 < 20%. Furthermore, we discover a deviation from the Zweifach—Fung effect which states that the child branch with lower flow rate recruits less RBCs than the higher flow rate child branch. At small enough (no, we get the inverse scenario, and the hematocrit in the lower flow rate child branch is even higher than in the parent vessel.

000014403 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000014403 653__ $$a

000014403 7112_ $$a24th International Congress of Theoretical and Applied Mechanics$$cMontreal (CA)$$d2016-08-21 / 2016-08-26$$gICTAM2016
000014403 720__ $$aCoupier, Gwennou
000014403 8560_ $$ffischerc@itam.cas.cz
000014403 8564_ $$s178572$$uhttps://invenio.itam.cas.cz/record/14403/files/TS.FM01-1.04.pdf$$yOriginal version of the author's contribution as presented on CD,  page 414, code TS.FM01-1.04
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000014403 962__ $$r13812
000014403 980__ $$aPAPER