000015087 001__ 15087
000015087 005__ 20161115100211.0
000015087 04107 $$aeng
000015087 046__ $$k2016-08-21
000015087 100__ $$adeBotton, Gal
000015087 24500 $$aMicromechanics motivated modeling of fibrous tissues

000015087 24630 $$n24.$$p24th International Congress of Theoretical and Applied Mechanics - Book of Papers
000015087 260__ $$bInternational Union of Theoretical and Applied Mechanics, 2016
000015087 506__ $$arestricted
000015087 520__ $$2eng$$aInvestigation of the mechanical behavior of biological tissues requires efficient computational tools to provide a reliable prediction of their response. Hence there is a pressing need for models that based on realistic representation of tissues from their microstructure up to the macroscopic level. Presently, the number of models available in the literature which thoroughly capture the structure of biological tissues is fairly small. Here, we propose a novel micromechanically-based model for biological tissues that accounts for the properties of the constituting components, their spatial distribution and morphology. To this end, a 3D periodic representative volume element of the tissue is constructed and its average response is determined. The model reveals that crimped collagen fibers are recruited such that the mechanical response admits stiffening under tension versus a much softer response under compression. This model is useful to determine the mechanical response of tissues while reducing experimental labor.

000015087 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000015087 653__ $$a

000015087 7112_ $$a24th International Congress of Theoretical and Applied Mechanics$$cMontreal (CA)$$d2016-08-21 / 2016-08-26$$gICTAM2016
000015087 720__ $$adeBotton, Gal
000015087 8560_ $$ffischerc@itam.cas.cz
000015087 8564_ $$s189495$$uhttps://invenio.itam.cas.cz/record/15087/files/TS.SM01-1.04.pdf$$yOriginal version of the author's contribution as presented on CD,  page 1663, code TS.SM01-1.04
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000015087 962__ $$r13812
000015087 980__ $$aPAPER