000015096 001__ 15096
000015096 005__ 20161115100211.0
000015096 04107 $$aeng
000015096 046__ $$k2016-08-21
000015096 100__ $$aWeitz, Dave
000015096 24500 $$aUniversal correlation between stiffness and volume for cells (INVITED)

000015096 24630 $$n24.$$p24th International Congress of Theoretical and Applied Mechanics - Book of Papers
000015096 260__ $$bInternational Union of Theoretical and Applied Mechanics, 2016
000015096 506__ $$arestricted
000015096 520__ $$2eng$$aThe stiffness of cells is commonly assumed to depend on the stiffness of their surrounding: bone cells are much stiffer than neurons, and each exists in surrounding tissue that matches the cell stiffness. In this talk, I will discuss new measurements of cell stiffness, and show that that cell stiffness is strongly correlated to cell volume. This affects both the mechanics and the gene expression in the cell, and even impacts the differentiation of stem cells. To probe the effects of gene expression, I will discuss lab-on-a-chip developments, using drop-based microfluidics, that provide a full gene expression analysis at the level of individual cells.

000015096 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000015096 653__ $$a

000015096 7112_ $$a24th International Congress of Theoretical and Applied Mechanics$$cMontreal (CA)$$d2016-08-21 / 2016-08-26$$gICTAM2016
000015096 720__ $$aWeitz, Dave
000015096 8560_ $$ffischerc@itam.cas.cz
000015096 8564_ $$s172030$$uhttps://invenio.itam.cas.cz/record/15096/files/TS.SM01-3.01.pdf$$yOriginal version of the author's contribution as presented on CD,  page 1679, code TS.SM01-3.01
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000015096 962__ $$r13812
000015096 980__ $$aPAPER