000015103 001__ 15103
000015103 005__ 20161115100211.0
000015103 04107 $$aeng
000015103 046__ $$k2016-08-21
000015103 100__ $$aBelay, Tsegay
000015103 24500 $$aThe role of line tension on budding formation induced by diffusion of proteins on lipid bilayer

000015103 24630 $$n24.$$p24th International Congress of Theoretical and Applied Mechanics - Book of Papers
000015103 260__ $$bInternational Union of Theoretical and Applied Mechanics, 2016
000015103 506__ $$arestricted
000015103 520__ $$2eng$$aWe investigate the effects of line tension at the lipid-protein domain interface on membrane budding formation which is assumed to be induced by surface diffusion of the trans-membrane proteins. The theoretical model for the mechanics of membrane shape transformation is described by a modified formulation of the Helfrich model in order to accommodate any nonlinear response of the membrane due to the diffusion of the trans-membrane proteins. The resulting shape equation is numerically solved for Non-Monge or general membrane surface representation. Our results show that line tension at the domain interface makes a significant contribution on a spherical-shape-like budding formation on weakly curved or flat lipid membrane. We show numerically that increasing the line tension facilitates the reduction of the interface diameter between the flat membrane and generated spherical bud, thus increasing the potential to pinch off the bud. Full details can be found in [1].

000015103 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000015103 653__ $$a

000015103 7112_ $$a24th International Congress of Theoretical and Applied Mechanics$$cMontreal (CA)$$d2016-08-21 / 2016-08-26$$gICTAM2016
000015103 720__ $$aBelay, Tsegay
000015103 8560_ $$ffischerc@itam.cas.cz
000015103 8564_ $$s68131$$uhttps://invenio.itam.cas.cz/record/15103/files/TS.SM01-4.03.pdf$$yOriginal version of the author's contribution as presented on CD,  page 1691, code TS.SM01-4.03
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000015103 962__ $$r13812
000015103 980__ $$aPAPER