000022864 001__ 22864
000022864 005__ 20220110134531.0
000022864 04107 $$aeng
000022864 046__ $$k2018-05-14
000022864 100__ $$aRufaqua, R.
000022864 24500 $$aThe biochemical process of lubricant film formation in joint replacement

000022864 24630 $$n24.$$pEngineering Mechanics 2018
000022864 260__ $$bInstitute of Theoretical and Applied Mechanics of the Cech Academy of Sciences, Prague
000022864 506__ $$arestricted
000022864 520__ $$2eng$$aThe main objective of this study is to clarify the biochemical reactions of the formation of the lubricating film between the head and the cup of the joint replacement. The chemical changes taking place within the proteins of synovial fluid constitute after joint replacements need to be observed. Film formation is also dependent on the pH of the solution and static and rolling conditions, viscosity, concentration of the solution and other mechanical properties of the total environmental condition of joint replacement. The chemical composition of synovial fluid is predominantly considered to explain the development of film on the ball. The experiment was conducted in ball-on-cup configuration in a hip joint simulator, where the ball was made of cobalt chromium molybdenum alloy and the cup was of optical glass. The used proteins albumin, Îłglobulin and bovine serum were the reactants of this process. To analyze the products of the reaction, Raman spectroscopic method was used to observe the changes among proteins. After the analysis of the Raman spectra, it is assumed heterogeneous catalysis process could be taken place on the metal ball during chemical reaction. The results could have significant information regarding lubricating film development within the joint replacement.

000022864 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000022864 653__ $$asynovial fluid, film formation, Raman spectroscopy, bio-tribology, tribo-chemistry

000022864 7112_ $$aEngineering Mechanics 2018$$cSvratka, CZ$$d2018-05-14 / 2018-05-17$$gEM2018
000022864 720__ $$aRufaqua, R.$$iet, al.
000022864 8560_ $$ffischerc@itam.cas.cz
000022864 8564_ $$s1052644$$uhttps://invenio.itam.cas.cz/record/22864/files/725.pdf$$yOriginal version of the author's contribution in proceedings, page , section BIO.
000022864 962__ $$r21225
000022864 980__ $$aPAPER