000004080 001__ 4080
000004080 005__ 20141118153336.0
000004080 04107 $$acze
000004080 046__ $$k2004-05-10
000004080 100__ $$aLebiš, R.
000004080 24500 $$aConstitutive model of vascular smooth muscle cells determined using computational simulation

000004080 24630 $$n10.$$pEngineering Mechanics 2004
000004080 260__ $$bInstitute of Thermomechanics AS CR, v.v.i., Prague
000004080 506__ $$arestricted
000004080 520__ $$2eng$$aIt is well known that vascular smooth muscle cells (VSMCs) play important role not only in vascular tone but also in arterial remodelling, healing and growth. Determination of mechanical properties of these cells is very important for understanding not only the physiology of VSMCs themselves but also the basic physiology, pathology, and mechanics of arterial wall. In the present study, a constitutive model of VSMCs of contractile and synthetic phenotypes is determined using FE computational simulation of tension tests of isolated cells. Material of the cells was modelled as homogeneous and isotropic using Mooney-Rivlin fiveparameter hyperelastic strain energy density function. The model was loaded similarly to the real experiment by micropipet displacement.

000004080 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000004080 653__ $$a

000004080 7112_ $$aEngineering Mechanics 2004$$cSvratka (CZ)$$d2004-05-10 / 2004-05-13$$gEM2004
000004080 720__ $$aLebiš, R.$$iHayashi, K.$$iBurša, J.
000004080 8560_ $$ffischerc@itam.cas.cz
000004080 8564_ $$s282016$$uhttps://invenio.itam.cas.cz/record/4080/files/T-Lebis-Radek.pdf$$y
             Original version of the author's contribution as presented on CD, .
            
000004080 962__ $$r4009
000004080 980__ $$aPAPER