000004953 001__ 4953
000004953 005__ 20141119144607.0
000004953 04107 $$aeng
000004953 046__ $$k2002-06-02
000004953 100__ $$aKatti, Kalpana
000004953 24500 $$aCONTROL OF MECHANICAL RESPONSES IN INSITU POLYMER-HYDROXYAPATITE COMPOSITES FOR BONE REPLACEMENT

000004953 24630 $$n15.$$pProceedings of the 15th ASCE Engineering Mechanics Division Conference
000004953 260__ $$bColumbia University in the City of New York
000004953 506__ $$arestricted
000004953 520__ $$2eng$$aPolymer-hydroxyapatite (HAP) composites are extensively studied for their potential use as bone replacement materials. In situ mineralization of HAP and the role of organics in initial nucleation and growth of HAP is critical for the resulting nano and microstructure of HAP. It is becoming increasing known that materials based on or mimicking biological structures exhibit far superior properties. In order to mimic biological processes, HAP is synthesized in the presence of polymeric additives. A molecular control of the crystallization of HAP to obtain desirable response of composite to loading is attempted. This work presents fundamental studies on the role of initial mineralization of HAP on bulk mechanical responses of composite. Fourier transform infrared attenuated total reflectance (FTIR ATR) spectroscopic experiments are undertaken to evaluate the association of polymeric chains with HAP during mineralization processes. Small changes are seen in the absorbance spectra of in situ HAP that relate to large differences in mechanical response of the composite to loading. Changes in mechanical response in the in situ composites include improved strain to failure and improved compressive strength under aqueous environment. In addition, smaller plastic strains are observed for in situ samples when subjected to cyclic loading. Our results may have significant implications in the design of biomaterials for biomedical applications

000004953 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000004953 653__ $$aBone, Nanocomposites, Hydroxyapatite, Polyacrylic Acid, FTIR.

000004953 7112_ $$a15th ASCE Engineering Mechanics Division Conference$$cNew York (US)$$d2002-06-02 / 2002-06-05$$gEM2002
000004953 720__ $$aKatti, Kalpana$$iGujjula, Praveen
000004953 8560_ $$ffischerc@itam.cas.cz
000004953 8564_ $$s1597549$$uhttps://invenio.itam.cas.cz/record/4953/files/607.pdf$$yOriginal version of the author's contribution as presented on CD, .
000004953 962__ $$r4594
000004953 980__ $$aPAPER