000008803 001__ 8803
000008803 005__ 20141204083522.0
000008803 04107 $$aeng
000008803 046__ $$k12/05/2014
000008803 100__ $$aJonášová, A.
000008803 24500 $$aSIMULATION OF CONTRAST MEDIUM PROPAGATION BASED ON 1D AND 3D PORTAL HEMODYNAMICS

000008803 24630 $$n20.$$pEngineering Mechanics 2014
000008803 260__ $$bBrno University of Technology- Institute of Solid Mechanics, Mechatronics and Biomechanics
000008803 506__ $$arestricted
000008803 520__ $$2eng$$aThe mathematical modelling of 3D blood flow coupled with contrast medium propagation in patient-specific human vessels ranks among the most computationally-demanding tasks, especially if a large vessel network is considered. With this in mind, some measure of simplification for potential use in clinical practice is usually inevitable and often also desired. In the present study, the main interest lies in the quantitative comparison between 3D and 1D models of portal hemodynamics and contrast medium propagation in two hepatic portal vein networks reconstructed from CT scans provided by the courtesy of the University Hospital Pilsen. To approximate the flow resistance of the downstream vascular bed and hepatic tissue, the mathematical model of Newtonian blood flow is coupled with the three-element Windkessel model. The numerical simulations of 3D and 1D blood flow and contrast medium propagation under average flow conditions are carried out using own in-house software. The obtained results show that, although the 1D model can never completely imitate the computational capabilities of the 3D model, its easy implementation, time-saving model preparation and almost no demands on computer technology dominate as advantages over obvious but moderate modelling errors arising from the dimensional reduction.

000008803 540__ $$aText je chráněný podle autorského zákona č. 121/2000 Sb.
000008803 653__ $$aPatient-specific model, Blood flow, Contrast medium, Finite volume method, Windkessel model.

000008803 7112_ $$aEngineering Mechanics 2014$$cSvratka (CZ)$$d12/05/2014 - 15/05/2014$$gEM2014
000008803 720__ $$aJonášová, A.$$iBublík, O.$$iRohan, E.$$iVimmr, J.
000008803 8560_ $$ffischerc@itam.cas.cz
000008803 8564_ $$s455572$$uhttps://invenio.itam.cas.cz/record/8803/files/53-Jonasova-CD.pdf$$yOriginal version of the author's contribution as presented on CD, paper No. 53.
000008803 962__ $$r70
000008803 980__ $$aPAPER