Yield-strain-energy is a better discriminator of hip fractures than BMD

Abstract eng:
Osteoporotic fracture is a major cause of suffering and disability for old people over the world. Accurate discrimination of high-risk patients is necessary to prevent osteoporotic fractures. Bone mineral density (BMD) measured by hip dual energy X-ray absorptiometry (DXA) is the gold standard reference recommended by the World Health Organization for screening osteoporosis, but it has limited accuracy in predict fracture risk. Clinicians are thus looking for more accurate tools such as biomechanical models. We proposed to use yield-strain-energy at the narrowest femoral neck (NFN-YSE) as a discriminator of hip fracture risk. NFN-YSE can be calculated from the subject’s hip DXA image using mechanical methods. A clinical cohort consisting of 195 hip fracture cases and 592 controls with matched sex and age was used to study the discrimination accuracy. The results show that NFN—YSE was more accurate than BMD in discriminating fractures from controls.

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