Spatial non-uniformity in the young’s modulus of the human eardrum

Abstract eng:
The eardrum plays an important role in transferring sound energy to the cochlea. Several recent studies have used inverse finite element (FE) methods to estimate the mechanical properties of the eardrum. However, the non-uniformity of the mechanical properties over the surface of the eardrum has not yet been reported. Our objective was to develop an approach to investigate the spatial non-uniformity of the ... imaged and compared with FE model simulations for optimization purposes. A modified Nelder-Mead optimization technique was used in this study. The effects of two types of eardrum partitioning on the optimization were studied and compared. Results showed that partitioning of the eardrum into 4 quadrants produces a closer match between simulated and experimentally measured deformations compared with the assumption of uniformity or with partitioning into concentric regions.

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