A study on imperfection sensitivity of pressured buckling of spherical virus shells

Abstract eng:
Motivated by the geometric heterogeneity inherent in spherical viruses, an imperfection sensitivity analysis is conducted based on a refined elastic shell model recently developed for spherical virus shells of high structural heterogeneity. The influence of key parameters of the refined model on imperfection sensitivity is examined. Our results show that the ratio of effective bending thickness to average shell thickness has a major effect, while the ratio of transverse shear modulus to in-plane shear modulus has a negligible influence on the imperfection sensitivity. In particular, with relevant parameters for typical imperfect spherical virus shells, the predicted buckling pressure could be roughly reduced to 55-65% of that of a prefect spherical virus shell.

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