Inertial microfluidics for manufacturing and quantitative single-cell studies (INVITED)

Abstract eng:
Inertial microfluidics is a field of study involving interactions between fluids with particles and/or fluids with structures where both inertia and viscosity become important. In traditional microfluidics, inertia has generally been ignored since the associated Reynolds number is close to zero due to the small channel scale and low flow velocity. However, cases with fluid flows that involve non-zero Reynolds numbers (i.e., non-zero inertia) are frequently encountered where fluid inertia should be accounted for. Inertial effects²inertial particle migration and secondary flow²have gained much attention in biology and medicine research because it inherently offers simple, sheathless, and highthroughput particle and cell manipulation that cannot be found in conventional active particle manipulation approaches. Through a deep understanding of fluid-particle-structure interactions, inertial microfluidics can be expanded to different fields, here in manufacturing and quantitative single-cell biology, in the sense of enabling technology.

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