3D characterization of acoustofluidic force fields in the fN range

Abstract eng:
One of the multifaceted techniques to handle functionalized beads and cells in ”Lab on a Chip” devices is acoustic particle manipulation. The characterization of the formed acoustic potential inside the micro channels is inaccessible by common methods, like microphones or pressure sensors. Therefore we developed an unique direct and contactless force sensor based on an optical trap to measure the acoustic forces on a single micro particle. A force resolution of 12 fN was reached for 2.06 ,am silica particles at 180 mW laser power. Up to 680 measurement points were realized and led to a 3D distribution of the acoustic force vector on a micro particle inside microfluidic channels and chambers.

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