On the Free Energy of Cells Spread on Micropatterned Substrates
Abstract eng: A new approach to the analysis of the spreading of cells on micro-pattemed substrates is presented. A thermodynamically consistent active cell model with non-local conservation of the total number of cell cytoskeletal proteins is used to simulate a range of spread states. The minimum free energy of the system is identified and corresponding stress fibre distributions are found to match experimental observations.
Publisher:
International Union of Theoretical and Applied Mechanics, 2016
Conference Title:
Conference Title:
24th International Congress of Theoretical and Applied Mechanics
Conference Venue:
Montreal (CA)
Conference Dates:
2016-08-21 / 2016-08-26
Rights:
Text je chráněný podle autorského zákona č. 121/2000 Sb.
Record appears in:
Record created 2016-11-15, last modified 2016-11-15
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