Zona pelucida as a mechano-responsive polymer
Abstract eng: Zona pelucida (ZP) is the most outer structure of mammalian oocytes and is important for gamete recognition, fertilization and integrity of the embryo. ZP is highly sulfated and glycosylated polymer gel that exhibit visco-elastic properties. Temperature, pH, ionic strength influences its biological function and aggregate state. We consider ZP as mechano-responsive polymer and proposed a new theory of fertilization based on coupled chemical²electrical fields and modeled ZP as a non-linear oscillatory reactive system. Analysis of its oscillatory states regarding external force is discussed.
Publisher:
International Union of Theoretical and Applied Mechanics, 2016
Conference Title:
Conference Title:
24th International Congress of Theoretical and Applied Mechanics
Conference Venue:
Montreal (CA)
Conference Dates:
2016-08-21 / 2016-08-26
Rights:
Text je chráněný podle autorského zákona č. 121/2000 Sb.
Record appears in:
Record created 2016-11-15, last modified 2016-11-15
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