Abstrakt:

The paper deals with problems related to computational modelling of stress-strain states in vascular smooth muscle cells (SMCs). Problems of their structure, geometry, co [...]

Mechanical stimuli represent a very important factor influencing cellular processes and functions. The knowledge about mechanical properties of cells is necessary for und [...]

The paper discusses a mathematical model of the isotonic smooth muscle contraction considering the influence of the excitation processes on the sarcolemma and inside the [...]

Abstrakt:

Abstrakt:

The transverse (T-) tubules of cardiac ventricular myocytes create a complex network of membrane invaginations. Many of the key proteins involved in excitation-contractio [...]

In this paper, a new description of intracellular Ca2+ dynamics in the model of rat ventricular cardiomyocyte is presented. The principal modifications based on the recen [...]

A novel quantitative model of a guin ea-pig ventricular myocyte has been designed with transverse-axial tubular system (TATS) included. This model displays long-term stab [...]

In this work, we present a new version of cardiac ventricular cell model incorporating the transverse - axial tubular system. The improvements include reformulated descri [...]

Abstrakt: The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggest [...]